Every day, 128 people in the United States die after an overdose involving prescription or illicit opioids; 1 in 4 Texans has experienced an overdose or know someone who has. The Texas Targeted Opioid Response, a public health initiative by the Texas HHSC, will assemble a panel to explore the Texas-sized effort to reduce opioid misuse and overdose among youth through public health programs - early childhood intervention, expanding access to naloxone, and safe disposal of unused medication.